When I gave a seminar last week in the Inorganic and Physical Chemistry department at IISc the slide that generated the most interest and discussion was the one below.
It shows how as one increases the number of deuterium atoms (replacing H) on the BEDT-TTF molecules (shown below) one gradually moves from the superconducting (S.C.) phase into the antiferromagnetic Mott insulator (A.F.I) phase.
This transition is analogous to what happens if one decreases the pressure or replaces the Br with Cl, i.e. it is generally associated with a change in the intermolecular spacings. Theory suggests this corresponds to increasing U/W [ratio of the Hubbard U to the bandwidth W]. It may also be due to a decrease in electronic frustration.
First, this must be a quantum nuclear effect (e.g. due to zero point motion) because the chemical forces [potential energy surfaces] for H and D are identical. This is the Born-Oppenheimer approximation.
Second, the relevant molecular orbitals are centred [i.e. have the dominant electronic density] on the S and C atoms and not the H atoms.
Third, one can expect some sort of geometric isotope effect where there are small changes in bond lengths and crystal lattice parameters with H to D substitution. However, generally these effects are very small, particularly for systems in which hydrogen bonding plays a small role. Here the H bonding is with the anion. Thus it is hard to see how these small geometric changes might produce large enough changes in the band structure parameters t and t' in the relevant Hubbard model.
Further insight might be gained by doing DFT-based calculations of the parameters t and t' for the geometries of the H and D crystals determined by x-ray diffraction.