I find it surprising that is almost three years since I my last post on this topic. I guess I try not to be too negative too often...
Vox has a very long article, The 7 biggest problems facing science, according to 270 scientists. It is worth reading and I largely agree with it. Possible concrete solutions are discussed. Many of the issues I have discussed on this blog and so it is both encouraging and discouraging to see others voice the same concerns.
I think a significant positive change would occur if the luxury journals (especially the pernicious Nature Publishing Group) were banned/boycotted and put out of business.
Funding agencies could simply say you can't use our money to do research that you publish in them. And in future applications you can't list any such publications from before 2017 on your CV.
I know it is not going to happen. But we do need to at least acknowledge that if it did that a lot of problems would be diminished.