Friday, December 14, 2012

Questions about protein folding

What is the physical code that relates the amino acid sequence to a proteins native structure?
How do proteins fold so fast?
Can protein structure be computationally predicted?

These are highlighted as key questions in a nice readable review in Science The Protein Folding problem, 50 years on by Ken Dill and Justin MacCallum.

The article gives a sober assessment of limited but significant achievements and the substantial challenges ahead.

1 comment:

  1. These are highlighted as key questions in a nice readable review in Science The Protein Characterization Folding problem, 50 years on by Ken Dill and Justin MacCallum.

    ReplyDelete

Philosophical perspectives on the emergence of molecular structure

 In philosophical discussions of emergence and reductionism in chemistry, molecular structure has received significant attention and debate....